Which Area Of Science Involves Animal Testing
The types of animal research carried out at the university range from:
i. Primal biology
Cardinal biological and medical enquiry helps us to identify key physiological mechanisms that control how our bodies work, effect wellness and affliction and that could lead to medical breakthroughs in the hereafter
2. Veterinary
To place and develop ways of assessing welfare in order to influence standards of care in farms and improve intendance of sick animals, such every bit developing ameliorate hurting relief in pet dogs with arthritis.
three. Translational
To develop better treatments for sick people or animals, such as implanting and testing new medical devices in farm species.
The types of studies our animals may be involved in include blood tests, behavioural studies and imaging. Other studies might involve surgery to implant monitoring devices that measure changes in the trunk, or new medical devices that could help salve human being lives.
Animals used in research
In 2021, the University carried out 27,437 scientific procedures using animals in enquiry regulated past the Animals (Scientific Procedures) Act 1986. The vast bulk of these involved rodents (41.1%) and fish (57.two%).
| Species | Procedures | Percentage | Employ |
|---|---|---|---|
| Mouse | 9,679 | 41.1% | Rodents play a vital function in helping us to answer a wide range of questions, including understanding fundamental aspects of our physiology, our genetic pathways and the mechanisms of affliction that support the development of future medicines and treatments for both humans and animals. |
| Rat | 1,601 | ||
| Zebrafish | 15,707 | 57.2% | Zebrafish let us to model the effects of cardiovascular illness, cancer and osteoarthritis as well as to report the genetic changes that can contribute to these debilitating diseases. They are incredibly good at regenerating cells, tissues and organs, something that we cannot do. By studying how they are able to do this we promise to observe better ways of treating people in the future. |
| Bat * | 215 | 0.viii% | We written report bats to assist with their conservation. Understanding their genetics could help us work out how we can protect them from the furnishings of global warming. |
| Grunter | 118 | 0.4% | Pigs and sheep tin can help usa develop new treatments and devices to do good both human being and animate being health. Pigs are besides used in studies of infectious disease to develop new vaccines for humans and better medicines for farm species in the future. |
| Sheep | 25 | 0.1% | |
| Guinea pig | 52 | 0.2% | Guinea pigs are used every bit a source of tissues for the study of aspects of physiology that are of import for improving patient treatment. |
| Rabbit | 40 | 0.1% | Rabbits are the most suitable species for our researchers to study important aspects of cardiac physiology that are key to improving our understanding and in the long-term patient treatment. |
* These procedures involved either customer owned or wild caught animals which were and then released at the end of the study.
Agreement our zebrafish and mice numbers
In 2021, the breeding of genetically altered (GA) animals deemed for 93% of our scientific procedures using zebrafish and 57% using mice. Breeding of GA animals is regulated under U.k. constabulary and is therefore counted like a scientific process.
- GA animals are important because specific changes in their genetic make-up enable researchers to discover and sympathize relationships between genes, physiology, and disease.
- Some of our research that benefits from the breeding of GA animals includes cancer, immunology, cardiology, osteoarthritis and human genetic disorders.
- Complex convenance cycles across multiple generations are essential to create these new GA animals before they can be used in a scientific study.
Find out more near the convenance of genetically altered animals on the Understanding Animal Research website.
Procedures on zebrafish
Procedures on mice
Previous years
2020
In 2020, the University carried out 22,681 scientific procedures using animals in research regulated by the Animals (Scientific Procedures) Act 1986. The vast majority of these involved rodents (48.3%) and fish (49.two%).
Due to SAR-CoV-ii, the number of animals used for research in 2020 is lower than in previous years. When the UK went into lockdown considering of the pandemic in March 2020, beast research studies were reduced due to the run a risk to animal welfare if staff were taken ill or had to self-isolate.
* These procedures involved either client owned or wild caught animals which were then released at the terminate of the report.
| Species | Procedures | Percentage |
|---|---|---|
| Mouse | 9,772 | 48.iii% |
| Rat | 1,188 | |
| Zebrafish | 11,162 | 49.2% |
| Bat * | 390 | 1.7% |
| Grunter | 91 | 0.5% |
| Sheep | xiv | |
| Republic of guinea hog | 35 | 0.2% |
| Rabbit | viii | 0.0% |
| Horses, donkeys and cantankerous-breeds (Equidae) | 21 | 0.i% |
2019
In 2019, the University carried out 28,652 scientific procedures using animals in research regulated by the Animals (Scientific Procedures) Act 1986. The vast majority of these involved rodents (53.2%) and fish (44.four%%).
| Species | Procedures | Per centum |
|---|---|---|
| Mouse | 12,763 | 53.ii% |
| Rat | two,487 | |
| Zebrafish | 12,726 | 44.4% |
| Bat | 461 | i.6% |
| Pig | 109 | 0.43% |
| Sheep | 10 | |
| Guinea grunter | 63 | 0.22% |
| Rabbit | 24 | 0.1% |
| Horses, donkeys and cross-breeds (Equidae) | 9 | 0.03% |
2018
In 2018, the Academy carried out 28,308 scientific procedures using animals in research regulated by the Animals (Scientific Procedures) Act 1986. The vast majority of these involved rodents (57.iv%) and fish (twoscore.16%).
| Species | Procedures | Pct |
|---|---|---|
| Mouse | 13,714 | 57.4% |
| Rat | 2,539 | |
| Zebrafish | 11,368 | twoscore.16% |
| Bat | 431 | 1.52% |
| Squealer | 106 | 0.4% |
| Sheep | 8 | |
| Republic of guinea pig | 63 | 0.22% |
| Xenopus | 28 | 0.12% |
| Rabbit | 35 | 0.12% |
| Rainbow trout | 16 | 0.07% |
2017
In 2017, the University carried out 26,090 scientific procedures using animals in inquiry regulated by the Animals (Scientific Procedures) Deed 1986. The vast bulk of these involved rodents (59%) and fish (36%).
| Species | Procedures | Pct |
|---|---|---|
| Mouse | 13,329 | 59% |
| Rat | 2,069 | |
| Zebrafish | 9,443 | 36% |
| Bat | 558 | 2.one% |
| Pig | 239 | 0.9% |
| Rainbow trout | 138 | 0.5% |
| Craven | 137 | 0.v% |
| Guinea pig | 87 | 0.iii% |
| Xenopus | 72 | 0.3% |
| Rabbit | 16 | 0.06% |
| Cat | ii | 0.008% |
2016
In 2016, the University carried out 26,990 scientific procedures using animals in research regulated by the Animals (Scientific Procedures) Deed 1986 . The vast majority of these involved rodents (63%) and fish (33%).
| Species | Procedures | Percentage |
|---|---|---|
| Mouse | xiii,472 | 63% |
| Rat | iii,462 | |
| Zebrafish | 8,964 | 33% |
| Bat | 323 | i.2% |
| Craven | 190 | 0.7% |
| Goat | 108 | 0.5% |
| Sheep | 39 | |
| Rabbit | 124 | 0.v% |
| Xenopus | 112 | 0.four% |
| Pig | 101 | 0.4% |
| Dog | 94 | 0.3% |
| Cat | 1 | 0.004% |
Source: http://www.bristol.ac.uk/animal-research/areas-we-study/
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